The dermo-cosmetics industry relies heavily on bioactive ingredients like synthetic peptides for their purported skin benefits, including anti-aging and wound healing. However, a significant issue within this field is the lack of comprehensive genetic validation for the mechanisms of action…
The integrity of the human stratum corneum (SC) is crucial for maintaining skin barrier function, primarily facilitated by a lipid matrix composed of ceramides, cholesterol, and free fatty acids. Among these lipids, ceramides exhibit the most molecular diversity, and their…
The pursuit of natural solutions for addressing concerns related to hair loss and skin aging has gained significant traction due to consumer demand for skin-friendly and safer alternatives to synthetic chemicals. The increasing prevalence of hair loss due to factors…
Acne vulgaris is a prevalent multifactorial skin disorder significantly impacting individuals both physically and psychologically. Characterized by the blockage of pilosebaceous follicle outlets and excessive keratin production, it creates an environment conducive to bacterial proliferation. Traditional approaches to acne treatment…
The cosmetics industry is witnessing a surge in demand for products that address not only aesthetic concerns but also contribute to overall well-being. Slimming cosmetics, in particular, have gained significant traction due to the increasing awareness of body image and…
Maintaining skin hydration is essential for barrier function, cell turnover, and overall skin health. Disruptions in the skin’s protective mechanisms can lead to dry, irritated, and compromised skin. Dermalayno is a topical daily skin repair moisturizing lotion designed to protect…
The gut microbiota, composed of a diverse range of microorganisms residing in the digestive tract, plays a pivotal role in maintaining human health, including the health of the skin. Disruptions in this microbial balance, known as gut dysbiosis, have been…
Sensitive skin is a prevalent issue arising from factors such as environmental pollution, unhealthy lifestyles, and autoimmune responses, often linked to the activation of the TRPV1 pathway and subsequent immune-inflammatory reactions. Individuals experiencing sensitive skin frequently encounter discomfort and irritation,…
The escalating threat of solar Ultraviolet (UV) radiation to human health, primarily through the generation of Reactive Oxygen Species (ROS) and induction of oxidative stress, necessitates the development of effective photoprotective strategies. While conventional sunscreen formulations containing chemical UV filters…
Chronic inflammation and oxidative stress are recognized as significant contributors to the development and progression of various debilitating diseases, including diabetes, cancer, and cardiovascular disorders. The search for natural products with potent anti-inflammatory, antioxidant, and antiglycation properties has gained considerable…