Cymbiotics

Cymbiotics

Eco-Friendly Enhancement of Ferulic Acid-Rich Extracts from Cnidium officinale and Angelica gigas via Hot-Melt Extrusion for Skin Brightening and Regeneration

Cnidium officinale (CO) and Angelica gigas (AG) are traditional medicinal herbs widely recognized in East Asian medicine for their diverse biological activities. Both herbs contain the bioactive compound ferulic acid (FA), a potent phenolic antioxidant known for its significant dermatological…

Efficacy and Safety of Zabedosertib, an Interleukin-1 Receptor-Associated Kinase 4 Inhibitor, in Patients with Moderate-to-Severe Atopic Dermatitis: A Phase II Randomized Study

Moderate-to-severe Atopic Dermatitis (AD) remains a challenging condition to treat, with existing therapeutic options often presenting limitations such as relapse after withdrawal, significant toxicities, or requiring parenteral administration. Conventional systemic immunosuppressants are associated with nephrotoxicity, myelosuppression, and gastrointestinal symptoms, while…