Introduction This study aimed to evaluate the potential of whole human saliva as an anti-acne agent against bacteria responsible for acne vulgaris (AV). Human saliva was selected due to its physiological and antioxidant properties, containing beneficial secretory molecules such as…
Our skin is more than just an outer covering – it’s a complex, multi-layered structure that plays a crucial role in protecting, regulating, and supporting our bodies. Comprising three main layers—the epidermis, dermis, and hypodermis—each layer has unique characteristics and…
The skin, the body’s largest organ, plays a crucial role in protecting internal tissues and regulating moisture and body temperature. However, it also presents a significant barrier to the penetration of many compounds, especially due to the structure of the…
Halobacteria trueperi TCI66207, an extremophilic microorganism thriving in high-salt environments, produces extracellular polysaccharides known for their promising anti-inflammatory, antioxidant, and anti-aging properties. This study focuses on the strain H. trueperi TCI66207, isolated from the Pacific Ocean at a depth of 662 m…
Agave sisalana, traditionally used in folk medicine for treating various ailments, discards 95% of its leaf biomass as waste. This study explores the potential of its sapogenin-rich residue, particularly hecogenin and tigogenin, for anti-inflammatory and analgesic uses. Steroidal saponins from…
Jujube (Ziziphus jujuba Mill.) extracts are rich in antioxidants and have potential anti-aging effects, targeting fine lines, wrinkles, and skin hydration. Key components include antioxidants, fatty acids, vitamins, and polysaccharides, which improve skin texture, promote collagen synthesis, regulate inflammation, protect…
Skin aging, accelerated by UV-induced reactive oxygen species (ROS), leads to wrinkles and loss of elasticity. Astaxanthin and zeaxanthin (AZ-NE), potent antioxidants, offer significant protection against ROS and have potential in anti-aging skincare. This study evaluates the stability, skin penetration,…
Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by epidermal barrier dysfunction, leading to increased transepidermal water loss and allergen entry, triggering inflammation. In India, AD affects 2.7% of children aged 6–7 years and 3.6% of adolescents aged…
Have you ever wondered why some areas of your skin feel different than others? It turns out that one of the biggest players in skin health is something you might not think about every day: your skin’s pH! Let’s dive…
Erlotinib, a tyrosine kinase inhibitor (EGFR-TKI), its use is frequently accompanied by significant cutaneous side effects, including facial dermatitis and hair loss. Previous research suggests that substance P (SP), a neuropeptide, is a major mediator of this skin toxicity. Given aprepitant’s…