The skin, as the body’s largest organ, plays a multifaceted role, functioning as a primary physical barrier, a central sensory organ, an immune system component, and an metabolically active tissue. Its integrity and function are significantly impacted by both internal…
Acne vulgaris is a widespread chronic inflammatory skin condition that affects individuals across various age groups, though it is most prevalent during adolescence and can persist or appear in adulthood. The complexity of acne’s pathogenesis involves several factors, including increased…
The skin microbiome is a critical player in maintaining skin health, influencing pH, lipid composition, and barrier integrity. In Brazil—home to one of the world’s largest cosmetics markets—women’s skin is shaped by unique ethnic diversity and a harsh tropical climate…
Bilberry (Vaccinium myrtillus L.) fruits are a recognized source of bioactive compounds with documented bioactivities. While bilberry fruits are commonly utilized, the leaves are frequently considered industrial by-products. However, recent studies have shown that bilberry leaves are also a valuable…
Skin dullness is a widespread dermatological concern, characterized by an uneven skin tone that often contributes to a fatigued and aged appearance, potentially making one look older than their biological age. This issue is influenced by both aging processes and…
Given the increasing demand for skin whitening and health products, tyrosinase inhibitors have garnered significant attention in the food, pharmaceutical, and cosmetic industries. However, conventional inhibitors like arbutin, hydroquinone, and kojic acid often face limitations due to issues with solubility,…
The cosmetic industry is experiencing a growing demand for natural and sustainable ingredients, driven by increasing consumer awareness regarding the potential concerns associated with synthetic compounds. Simultaneously, the human skin’s microbiome, while crucial for health, can also harbor pathogenic organisms…
Skin health is closely tied to collagen production, which maintains firmness and elasticity. Cell therapies often leverage the “secretome,” a cocktail of growth factors, proteins, and signaling molecules released by cells. Among these, extracellular vesicles (EVs)—especially bacterial EVs (bEVs)—have emerged…
Skin injuries, from simple cuts to chronic ulcers, affect up to 6% of the population and often result in poor healing due to infection, oxidative stress, and extracellular matrix breakdown. Chronic wounds are particularly challenging, often complicated by biofilm-forming fungi…
Consumers are increasingly shifting toward clean-label skincare, pressuring formulators to replace synthetic preservatives and antioxidants. While conventional additives like parabens and formaldehyde releasers offer some protection, they come with safety concerns—including irritation, allergies, cytotoxicity, and environmental burden. The need for…