Historically, hemp leaves (Cannabis sativa L.) have been discarded as agricultural waste because they contain lower concentrations of cannabidiol (CBD) compared to the plant’s flowers. However, the substantial biomass produced per plant presents a cost-effective opportunity for the cosmetic industry…
The human skin is a dynamic ecosystem where a balanced microbial community maintains barrier integrity and prevents pathogen colonization. However, injuries and external factors can lead to dysbiosis, an imbalance that allows opportunistic “ESKAPE” pathogens—such as Staphylococcus aureus and Pseudomonas…
Inflammation and skin wound healing represent complex biological responses essential for restoring tissue integrity; however, chronic or dysregulated inflammation can severely impede this process. Current clinical treatments often rely on synthetic pharmacotherapies like corticosteroids and non-steroidal anti-inflammatory drugs (NSAIDs), which…
The search for natural bioactive components to treat human ailments is a continuous challenge in modern medicine and dermatology. While traditional knowledge has long recognized the therapeutic properties of plants, there is a significant need for scientific validation and detailed…
Brazil faces high levels of ultraviolet radiation (UVR) exposure, posing significant public health risks; however, individuals with darker skin (phototypes IV-VI) are frequently underrepresented in photoprotection research. A common misconception that Black skin is inherently resistant to UVR damage often…
Pomegranate peel, a significant agro-industrial by-product, is rich in bioactive polyphenols like punicalagin, which offers potent antioxidant and photoprotective benefits. However, the dermal delivery of these compounds is hindered by their high molecular weight, hydrophilic nature, and susceptibility to degradation,…
The global prevalence of chronic skin conditions such as atopic dermatitis, psoriasis, and premature aging has increased significantly, often driven by interdependent processes of local oxidative stress and dysregulated inflammation. Conventional synthetic treatments can sometimes lead to adverse effects, prompting…
The cosmetic industry is increasingly shifting toward natural, marine-derived ingredients due to safety concerns regarding synthetic antioxidants and the need for multifunctional anti-aging solutions. Skin aging is a complex process characterized by oxidative stress, reduced epidermal moisture, and the structural…
Skin aging is characterized by the structural deterioration of the dermal extracellular matrix, primarily driven by oxidative stress from reactive oxygen species (ROS). This stress triggers an imbalance where type I collagen synthesis is suppressed and degradation is accelerated by…
Extrinsic skin aging is largely driven by environmental stressors like ultraviolet (UV) radiation and heat, which account for up to 90% of visible skin changes including wrinkles, loss of elasticity, and hyperpigmentation. These factors generate reactive oxygen species (ROS) that…