The health and appearance of human skin are significantly impacted by environmental factors, particularly ultraviolet (UV) radiation, which is estimated to be responsible for 90% of skin aging. UV-A rays, making up approximately 95% of the UV radiation reaching Earth,…
Acne vulgaris is a chronic inflammatory skin disorder that affects approximately 85% of individuals aged 12–24, often leading to significant psychosocial impacts like anxiety and depression. While conventional treatments such as retinoids and antibiotics are standard, they frequently cause localized…
Extended exposure to ultraviolet (UV) radiation is a significant health risk, leading to detrimental effects on human skin. While the global market for sun protection is growing, many current commercial sunscreens rely on inorganic filters like zinc oxide and titanium…
Aesthetic interventions using energy-based devices (EBDs), such as fractional CO2 laser (FCL) and radiofrequency microneedling (RFMN), rejuvenate skin by inducing controlled thermal injury to stimulate dermal remodeling. However, these procedures inherently cause transient side effects, including erythema, edema, and compromised…
The rapid growth of the prickly pear (Opuntia ficus-indica) oil industry has created a significant environmental and economic challenge: the generation of massive volumes of agro-industrial by-products. While the seeds yield only 5–10% oil, the remaining 90–95% of biomass is…
The traditional understanding of skin aging has recently expanded to include porphyr’ageing, a phenomenon where porphyrins—metabolites produced by skin microbiota like Cutibacterium acnes—contribute to visible senescence,. These pro-inflammatory molecules, particularly coproporphyrin III, penetrate the skin to trigger melanin synthesis, induce…
Acne vulgaris remains a pervasive dermatological challenge characterized by overactive innate immune responses, massive leukocyte infiltration, and subsequent tissue damage or scarring. While various treatments exist, there is an increasing demand for safe, effective, and plant-derived candidates to manage acne-prone…
Wounds, defined as disruptions in tissue integrity, become a significant medical burden when they transition into chronic states that fail to heal due to physiological conditions or persistent infections. A critical global challenge is the rising drug resistance against conventional…
The clinical management of cutaneous wounds remains a significant challenge, as factors such as diabetes, advanced age, and vascular insufficiency often lead to chronic, non-healing ulcers. These conditions are associated with high patient morbidity and mortality, yet current treatments—such as…
The cosmetic industry faces an increasing need for sustainable, locally produced ingredients capable of withstanding shifting environmental conditions caused by global warming. While the cultivated olive tree (Olea europaea var. europaea) is prized for its bioactive leaves rich in antioxidants…