Maintaining skin hydration is essential for barrier function, cell turnover, and overall skin health. Disruptions in the skin’s protective mechanisms can lead to dry, irritated, and compromised skin.
Dermalayno is a topical daily skin repair moisturizing lotion designed to protect chafed, chapped, or cracked skin. Uniquely formulated by Cymbiotics, it targets the root causes of dry skin and provides lasting relief.
Understanding Dry Skin: More Than Just a Surface Issue
Dry skin results from structural and functional impairments in the stratum corneum, leading to increased moisture loss and barrier dysfunction. A key contributor is Trans Epidermal Water Loss (TEWL), where the skin loses water at a higher rate than it can retain. Essential fatty acid deficiency and genetic differences can compromise hydration and overall barrier integrity. Environmental stressors (like UV exposure, harsh chemicals) and hormonal shifts further exacerbate dryness.
For mild cases of dry skin, using a moisturizing lotion or cream often help restore hydration and strengthen the skin barrier.
Skin Cell Renewal and the Role of Hydration
The outermost layer of the skin, the epidermis, is constantly undergoing renewal. Skin cells (keratinocytes) originate in the basal layer and gradually move upward through the epidermis, undergoing structural changes before shedding from the surface.
When the skin is adequately hydrated, this renewal process functions optimally, leading to healthy, resilient skin. However, dryness slows down this natural exfoliation process, causing dead skin cells to accumulate, leading to flaking, rough patches, and an overall dull complexion.
A well-formulated moisturizer, like Dermalayno, helps maintain proper hydration, ensuring that the skin’s renewal cycle remains efficient and that new, healthy cells reach the surface smoothly.
Why Enhancing Transdermal Flux Matters for Dry Skin
Dry skin results from skin barrier dysfunction, leading to increased transepidermal water loss (TEWL) and impaired hydration. This is where transdermal flux comes in.
Transdermal flux refers to the rate at which active ingredients penetrate the skin and reach the underlying layers. Enhancing transdermal flux is crucial for improving ingredient absorption and restoring skin hydration, especially in cases of dryness and barrier damage.
There are two ways to enhance transdermal flux:
- System Innovations – These utilize mechanical or energy-based methods (such as microneedles or ultrasound) to enhance penetration.
- Formulation Innovations – These modify the delivery system itself to optimize absorption without the need for external devices.
Cymbiotics’ Fast Acting Dermal Delivery (FADD) is a formulation innovation, it employs a proprietary blend of penetrant molecules and polar solvents that form the Cetylated Fatty Ester Penetrant Complex (CFEP-complex). This complex leverages cetylated fatty esters (as) penetration enhancers (CPE), optimizing ingredient delivery for superior hydration and repair.
C- Cetylated fatty ester
P- Penetration
E- Enhancers
Fast Acting Dermal Delivery (FADD) Technology: Delivering Results Where You Need Them
Cymbiotics’ novel Fast Acting Dermal Delivery (FADD) Technology, a specialized system designed to accelerate skin healing and enhance the penetration of ingredients into or through the dermal layers to ensure targeted and efficient dermal delivery. This technology serves as the key differentiator of Dermalayno.
What is FADD Technology?
FADD is a transdermal delivery system that helps health-promoting components bypass the skin’s natural barrier resistance. It is formulated using a combination of essential penetrant molecules and polar solvents, which work together to improve the absorption of pharmaceutical or cosmetic active agents.
Key Components of FADD Technology
- Penetration Enhancers
A vital component of the FADD system is the Penetration Enhancers, consisting of a mixture of cetylated fatty acid esters and polar solvents. When properly prepared during manufacturing, these form the Cetylated Fatty Ester Penetrant Complex (CFEP-complex). The CFEP-complex serves as the fundamental transport mechanism within the FADD system, facilitating the movement of active compounds through the skin barrier.
- Aqueous Suspension Solution
The aqueous suspension solution is another crucial component of the FADD system. It acts as the carrier medium, maintaining product stability and ensuring the even distribution of ingredients when applied to the skin.
Additional Enhancing Components
Although the CFEP-complex forms the base delivery component of the FADD system, other components are incorporated to further enhance the efficacy of ingredient delivery.
- Antioxidants – to maintain the stability of active ingredients and protect them from oxidative degradation.
- Silicones – to aid in ingredient retention, enhance barrier protection, and optimize the absorption of actives.
These additional components work synergistically with the primary elements of the FADD system to ensure targeted and efficient dermal delivery, maximizing the benefits of Dermalayno’s formulation.
Dermalayno’s Key Ingredients
Cymbiotics Dermalayno’s effectiveness is in its carefully selected ingredients that work synergistically to restore and protect your skin:
- Allantoin – Acts as a moisturizer to treat or prevent dry, rough, scaly, and itchy skin and minor skin irritations. It also stimulates healthy tissue formation and gently cleanses the skin.
- Glycerin – Known for its humectant properties, it enhances skin hydration and supports barrier repair. It increases the fluidity of lipid bilayers and helps the skin retain moisture.
- Oat Beta Glucan – Stimulates the immune system and promotes cellular activity, which can lead to a reduction in fine lines and wrinkles. It acts as a natural moisture barrier.
- Oatmeal extract- Soothes irritated skin, reduces redness, and relieves itching. It also helps strengthen the skin barrier and lock in moisture for lasting hydration.
- Soy Protein – Offers cleansing, moisturizing, and pigmentation-improving benefits for the skin.
- Vitamin E – Dermalayno contains antioxidants in the form of Vitamin E, to neutralize free radicals and prevent cellular damage.
Conclusion
Dry, irritated skin often results from a weakened skin barrier and insufficient moisture retention, necessitating effective topical formulations that restore hydration and support skin renewal. Dermalayno is designed with a carefully selected combination of moisturizing agents, antioxidants, and Fast Acting Dermal Delivery (FADD) Technology, ensuring enhanced penetration of active ingredients for optimal skin repair. By leveraging this innovative transdermal system, Dermalayno provides a targeted approach to maintaining skin hydration, promoting a healthy epidermal barrier, and improving overall skin resilience.
Marketed Variant
Dermalayno is marketed under the brand name Epilyno by Sun Pharma, a well-established product recognized for its effectiveness in managing dry and irritated skin. Epilyno has gained widespread success due to its advanced formulation. With its unique blend of moisturizing agents with our proprietary Fast Acting Dermal Delivery (FADD) Technology. This scientifically formulated approach offers a reliable solution for skin repair, enhanced hydration, and barrier support.
