The skin, the body’s largest organ, plays a crucial role in protecting internal tissues and regulating moisture and body temperature. However, it also presents a significant barrier to the penetration of many compounds, especially due to the structure of the…
Halobacteria trueperi TCI66207, an extremophilic microorganism thriving in high-salt environments, produces extracellular polysaccharides known for their promising anti-inflammatory, antioxidant, and anti-aging properties. This study focuses on the strain H. trueperi TCI66207, isolated from the Pacific Ocean at a depth of 662 m…
Agave sisalana, traditionally used in folk medicine for treating various ailments, discards 95% of its leaf biomass as waste. This study explores the potential of its sapogenin-rich residue, particularly hecogenin and tigogenin, for anti-inflammatory and analgesic uses. Steroidal saponins from…
Jujube (Ziziphus jujuba Mill.) extracts are rich in antioxidants and have potential anti-aging effects, targeting fine lines, wrinkles, and skin hydration. Key components include antioxidants, fatty acids, vitamins, and polysaccharides, which improve skin texture, promote collagen synthesis, regulate inflammation, protect…
Skin aging, accelerated by UV-induced reactive oxygen species (ROS), leads to wrinkles and loss of elasticity. Astaxanthin and zeaxanthin (AZ-NE), potent antioxidants, offer significant protection against ROS and have potential in anti-aging skincare. This study evaluates the stability, skin penetration,…
Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by epidermal barrier dysfunction, leading to increased transepidermal water loss and allergen entry, triggering inflammation. In India, AD affects 2.7% of children aged 6–7 years and 3.6% of adolescents aged…
Erlotinib, a tyrosine kinase inhibitor (EGFR-TKI), its use is frequently accompanied by significant cutaneous side effects, including facial dermatitis and hair loss. Previous research suggests that substance P (SP), a neuropeptide, is a major mediator of this skin toxicity. Given aprepitant’s…
Acne is one of the most prevalent skin disorders worldwide, affecting millions across various age groups. Primarily caused by the bacterium Propionibacterium acnes. Various treatments exist, from topical agents to oral medications, but many suffer from limitations such as side…
IntroductionThe skin, as the largest organ of the body, is a complex barrier that protects against a variety of external threats, including UV exposure, pathogens, and environmental pollutants. Despite its resilience, the skin is vulnerable to a range of conditions…
Introduction Natural products, particularly marine-derived compounds, have garnered increasing attention as alternatives to conventional treatments for inflammatory skin diseases. Traditional anti-inflammatory therapies, such as corticosteroids and immunomodulators, often come with limitations and side effects, driving the need for safer, natural…