Hyperpigmentation disorders are prevalent and distressing conditions characterized by the excessive secretion of melanin in the epidermis and/or dermis. Among these, post-inflammatory hyperpigmentation (PIH), which involves skin darkening resulting from inflammation and subsequent activation of melanogenesis by inflammatory mediators, represents…
The cosmetic industry, a significant sector of the global economy, has seen substantial advancements in formulation and technology, driven by increasing consumer concerns regarding skin aging, dermatological imperfections, and conditions like acne and skin cancer. This heightened awareness has spurred…
The human skin harbors a complex ecosystem of bacteria, fungi, and viruses, collectively known as the skin microbiome, which is crucial for maintaining skin health, immunity, and overall appearance. This intricate balance protects the skin barrier from infections and pathogenic…
Maintaining skin health, particularly through proper moisturization, is increasingly recognized as fundamental in the rapidly growing cosmetics industry. Consumers widely utilize skin moisturizers to preserve youthful, hydrated skin, prevent dryness, and reduce transepidermal water loss (TEWL). These products are crucial…
The cosmetics industry is increasingly driven by consumer demand for eco-friendly, natural ingredients that offer diverse biological activities. This shift highlights a pressing need for alternatives to synthetic additives, which contribute to environmental micropollutants. Microalgae and cyanobacteria, often regarded as…
The health and appearance of nails, hair, and skin are critical for human well-being and self-expression, yet factors like aging, stress, and diseases often lead to unmet needs in their quality. Silicon (Si), a significant trace element, is crucial for…
Cnidium officinale (CO) and Angelica gigas (AG) are traditional medicinal herbs widely recognized in East Asian medicine for their diverse biological activities. Both herbs contain the bioactive compound ferulic acid (FA), a potent phenolic antioxidant known for its significant dermatological…
The cosmetics industry has seen a significant expansion in the market for personalized cosmeceutical preparations, which offer enhanced benefits over conventional cosmetics by integrating bioactive ingredients with clinically proven therapeutic effects. These next-generation topical platforms are specifically designed to deliver…
Moderate-to-severe Atopic Dermatitis (AD) remains a challenging condition to treat, with existing therapeutic options often presenting limitations such as relapse after withdrawal, significant toxicities, or requiring parenteral administration. Conventional systemic immunosuppressants are associated with nephrotoxicity, myelosuppression, and gastrointestinal symptoms, while…
Niacinamide, also known as nicotinamide, is a form of vitamin B3 (part of the vitamin B3 family which includes nicotinic acid and nicotinamide riboside) that is not endogenously synthesized by the body. Once absorbed, these forms are converted into nicotinamide…