Category Scientific Updates

Microbial Fermentation Potentiates the Multifunctional Skin-Care Activities of Polianthes tuberosa L. Flower Extract: Antioxidant, Anti-Glycation, and Anti-Melanogenic Effects

The skin, as the largest organ of the human body, is consistently subjected to environmental stressors like ultraviolet (UV) radiation and pollution. These stressors lead to oxidative stress, which is a primary driver of accelerated skin aging, manifesting as wrinkles,…

Read MoreMicrobial Fermentation Potentiates the Multifunctional Skin-Care Activities of Polianthes tuberosa L. Flower Extract: Antioxidant, Anti-Glycation, and Anti-Melanogenic Effects

Cosmeceutical Potential of Mitragyna speciosa (Kratom): Anti-Adipogenic and Antioxidant Properties of Extracts and Mitragynine

The Issue and the Potential Solution Kratom (Mitragyna speciosa (Korth.) Havil.) is a medicinal plant known for containing bioactive alkaloids, such as mitragynine, which historically provide stimulant and analgesic effects. However, significant safety concerns, especially regarding potential adverse effects at…

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Long-Term Safety and Efficacy of Roflumilast Foam 0.3% in Patients with Seborrheic Dermatitis: A Phase II, Open-Label Trial of up to 52 Weeks

Seborrheic dermatitis (SD) is a prevalent, chronic relapsing inflammatory skin condition that affects patients of all ages, with a global prevalence of ≥ 5%. Patients suffering from SD typically develop pruritic, erythematous patches that feature easily detachable scales, primarily in…

Read MoreLong-Term Safety and Efficacy of Roflumilast Foam 0.3% in Patients with Seborrheic Dermatitis: A Phase II, Open-Label Trial of up to 52 Weeks

A Polyherbal Formulation That Mitigates Cellular Damage in Narrowband UVB-Irradiated HaCaT Cells

Narrowband ultraviolet B (NB-UVB) phototherapy is a commonly used treatment for various skin diseases, including vitiligo, psoriasis, eczema, and photodermatoses. While effective, prolonged use of NB-UVB carries significant adverse effects, notably inducing skin aging, inflammation, and reduced cell viability. The…

Read MoreA Polyherbal Formulation That Mitigates Cellular Damage in Narrowband UVB-Irradiated HaCaT Cells

Formulation and Evaluation of a Natural Face Serum Utilizing Clitoria Ternatea and Manjistha

The field of cosmetology is increasingly shifting focus towards natural products and away from artificial ones, driven by a growing consumer demand for plant-based skincare alternatives. While the skin, the body’s largest organ, constantly attempts self-repair, environmental stressors like pollution,…

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Development of a Novel Curcuma aromatica Extract-Loaded Hydrogel Patch for Anti-Acne and Anti-Inflammation

Inflammatory skin disorders, including dermatitis, eczema, psoriasis, and acne, are pervasive dermatologic illnesses that significantly impact patients’ quality of life and health. Acne, a highly common condition, involves a complex pathology including sebum alteration, aberrant follicular keratinization, and the presence…

Read MoreDevelopment of a Novel Curcuma aromatica Extract-Loaded Hydrogel Patch for Anti-Acne and Anti-Inflammation

Phyto-Assisted Synthesis and Investigation of Zinc Oxide Nanoparticles for Their Anti-Aging, Sun Protection and Antibacterial Activity

Skin aging is an inevitable biological phenomenon often accelerated by chronic exposure to harmful external influences, particularly ultraviolet (UV) radiation, which leads to extrinsic aging, or photoaging. Photoaging causes the deterioration of skin quality through the generation of reactive oxygen…

Read MorePhyto-Assisted Synthesis and Investigation of Zinc Oxide Nanoparticles for Their Anti-Aging, Sun Protection and Antibacterial Activity

Persicaria tinctoria Extract Mitigates UV-Associated DNA Damage and Inflammation, While Boosting Vitamin D3 and Melanin in Human Skin

The management of human skin exposure to sunlight, particularly ultraviolet (UV) rays, involves balancing the risks of photodamage with the physiological necessity of UV-related metabolic pathways. UV radiation, composed mainly of UVA and the more energetic UVB, is the leading…

Read MorePersicaria tinctoria Extract Mitigates UV-Associated DNA Damage and Inflammation, While Boosting Vitamin D3 and Melanin in Human Skin

Evaluation, Symptoms, Influencing Factors, and Prospects of Sensitive Scalp

Sensitive scalp (SSC) represents a frequent yet often overlooked dermatological state. It is primarily defined by the occurrence of abnormal and unpleasant sensory reactions—such as pruritus (itching), stinging, tightness, pain, and burning sensations—in response to typical environmental stimuli. These sensations…

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Efficacy and Safety of a Novel Anhydrous 0.1% Retinal-Based Concentrate for Photoaged Skin

Skin aging is a complex biological phenomenon influenced by intrinsic factors (like genetics and cellular decline) and extrinsic factors, among which ultraviolet (UV) radiation-induced photoaging is considered the most significant contributor. Photoaging leads to the production of reactive oxygen species…

Read MoreEfficacy and Safety of a Novel Anhydrous 0.1% Retinal-Based Concentrate for Photoaged Skin