Skin aging is a complex biological process significantly driven by Reactive Oxygen Species (ROS) and mitochondrial dysfunction. The skin, as the body’s largest organ, constantly renews itself and requires substantial adenosine triphosphate (ATP) produced by mitochondria. During aging, ROS are…
Chronic dermatological conditions, notably acne vulgaris, androgenetic alopecia (AGA), and alopecia areata (AA), represent a significant burden worldwide, affecting hundreds of millions of individuals and substantially impairing quality of life. Acne alone ranks among the leading causes of disability-adjusted life…
Skin is more than a barrier, it’s a bustling biological economy. Every second, its cells are spending, saving, and regenerating energy to keep the surface you see functioning as a dynamic, self-repairing organ. From wound healing to barrier restoration, every process…
Curcumin (Cur), a naturally occurring polyphenolic compound derived from Curcuma longa, is highly valued in cosmeceutical formulations due to its potent anti-inflammatory and antioxidant properties. Cur plays a multifaceted role in skincare, helping to protect against oxidative stress and premature…
Skin disorders such as photoaging, sunburn, hyperpigmentation, and carcinogenesis represent significant global health and cosmetic challenges, especially as exposure to ultraviolet (UV) radiation intensifies. Sunscreen formulations are essential tools designed to prevent photodamage and deliver therapeutic benefits. However, the reliance…
Acne is a pervasive skin disorder linked to the pilosebaceous components of the skin (hair follicles and oil glands). It manifests clinically through seborrhea and inflammatory or non-inflammatory lesions, often resulting in scarred skin. Acne is highly prevalent among adolescents,…
Epidermal photoinflammation has been identified as an atypical pathological response that poses a growing global threat to human health and well-being. The skin’s protective barrier, primarily relying on the stratum corneum, is disrupted by excessive external stimuli. Among these stimuli,…
Skin aging is driven by both intrinsic chronologic processes and extrinsic factors, primarily photoaging due to ultraviolet (UV) exposure. This degradation manifests as wrinkles, sagging, laxity, and uneven texture, underpinned by structural changes in the extracellular matrix (ECM). Critical components…
Our skin speaks the language of emotion. From blushing under stress to breaking out before an important event, the link between mental health and skin function runs deeper than we often realize. This hidden dialogue between the skin and the…
Ginkgo biloba L. leaves contain important bioactive compounds, including flavonoids, organic acids, and terpenoids, and extracts from the plant have traditionally been used in medicine. Recently, Ginkgo biloba extracts have garnered renewed attention for their potential benefits, particularly in protecting…