Month December 2025

Non-Invasive Imaging to Detect the Effects of Topical N-Butanoyl Glutathione (GSH-C4) and Hyaluronic Acid in Inflammatory Eczematous Dermatitis

Eczematous dermatitis encompasses a variety of inflammatory skin disorders—such as seborrheic dermatitis, atopic dermatitis, and contact dermatitis—that are primarily characterized by chronic inflammation and dysfunction of the epidermal barrier. A core goal in managing these conditions is improving patient outcomes…

Read MoreNon-Invasive Imaging to Detect the Effects of Topical N-Butanoyl Glutathione (GSH-C4) and Hyaluronic Acid in Inflammatory Eczematous Dermatitis

Anti-Aging Evaluation of Cosmetics on a Tri-Layered Chitosan Membrane: An Alternative to Animal Testing

Physical appearance, particularly related to the face, is a significant social factor, and the visible manifestation of age-related changes increasingly impacts psychological well-being. Reflecting this widespread concern, the global anti-aging skincare market was valued at USD 62.6 billion in 2021…

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Shotgun metagenomics reveals distinct skin microbial species in allergen- sensitized individuals

The global prevalence of allergic diseases has increased dramatically, paralleling the rapid urbanization and modernization that followed World War II. This shift toward urban living has led to a dramatic reduction in human exposure to biodiverse and natural environments. According…

Read MoreShotgun metagenomics reveals distinct skin microbial species in allergen- sensitized individuals

Evaluation of the Degree of Melasma Reduction After Application of a Chemical Skin Stimulation Product in Combination with a Lightening Serum

Melasma is a chronic hyperpigmentation disorder that often proves resistant to therapy. It is recognized as one of the most challenging aesthetic defects to treat, characterized by irregular, well-demarcated discoloration spots typically found on the face, which intensify upon exposure…

Read MoreEvaluation of the Degree of Melasma Reduction After Application of a Chemical Skin Stimulation Product in Combination with a Lightening Serum

Decoding Gut Microbiome Dysbiosis as a Non-Invasive Diagnostic Biomarker for Alopecia Areata

Alopecia areata (AA) is a common, chronic autoimmune disorder characterized by non-scarring hair loss that significantly affects approximately 2% of the global population. The disease imposes a substantial psychosocial burden, often linked to anxiety and depression. Pathogenically, AA is driven…

Read MoreDecoding Gut Microbiome Dysbiosis as a Non-Invasive Diagnostic Biomarker for Alopecia Areata

Investigation into the Delivery and Evaluation of a Unique Avena sativa (Oat) Lipid Extract on Skin Barrier

The integrity of the skin’s protective and regulatory barrier function is primarily achieved within the stratum corneum (SC), the outermost layer of the epidermis. The SC utilizes a “brick-and-mortar” structure where corneocytes (bricks) are embedded in a matrix of highly…

Read MoreInvestigation into the Delivery and Evaluation of a Unique Avena sativa (Oat) Lipid Extract on Skin Barrier

Investigating the Biological Activities of Sapindus mukorossi Seed Hydrosol and its Potential as a Skincare Ingredient

Traditional and modern applications recognize the therapeutic potential of Sapindus mukorossi (S. mukorossi), commonly known as the soapnut tree, particularly for skin care and wound treatment. Extracts from the fruit pericarp and seed oil of S. mukorossi have shown promising…

Read MoreInvestigating the Biological Activities of Sapindus mukorossi Seed Hydrosol and its Potential as a Skincare Ingredient