Category Scientific Updates

Topical Application of Aprepitant Inhibits Erlotinib-induced Facial Dermatitis and Hair Loss

Introduction Erlotinib, a tyrosine kinase inhibitor (EGFR-TKI), its use is frequently accompanied by significant cutaneous side effects, including facial dermatitis and hair loss.  Previous research suggests that substance P (SP), a neuropeptide, is a major mediator of this skin toxicity. Given…

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Investigating the Anti-Inflammatory Activity of Various Brown Algae Species 

Introduction  Natural products, particularly marine-derived compounds, have garnered increasing attention as alternatives to conventional treatments for inflammatory skin diseases. Traditional anti-inflammatory therapies, such as corticosteroids and immunomodulators, often come with limitations and side effects, driving the need for safer, natural…

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The Skin Care Potential of Garcinia latissima Miq. : A Natural Source for Elasticity and Brightness

Garcinia latissima Miq., native to Southeast Asia’s tropical rainforests, is a plant known for its rich source of phenolic compounds with antioxidant, antibacterial, and antimicrobial properties. Researchers in this review, explored its potential as a cosmetic ingredient, focusing on its…

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Harnessing the Power of Ginseng: A Comprehensive Review of Its Potential for Skincare and Skin Health

The skin is the body’s largest organ, playing vital roles in protection, regulation, and sensation. Constantly exposed to environmental factors like UV radiation and pollutants, the skin can be prone to aging, dehydration, and disease. As skincare evolves, one natural…

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Effect of Staphylococcus aureus Colonization and Immune Defects on the Pathogenesis of Atopic Dermatitis

Atopic dermatitis (AD) is a chronic skin disease marked by inflammation, pruritus (itchiness), and skin barrier dysfunction. While the exact cause of AD is unclear, epidermal barrier impairment, immune dysregulation, microbial imbalance (dysbiosis), and environmental triggers play key roles in…

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Fact-checking Cosmetic Trends: Systematic Review of the Use of Topical Astragalus Derivatives to Treat Dermatologic Conditions

Astragalus, a genus with over 2000 species, has been used in traditional Chinese medicine for centuries. Known for its diverse health benefits, is believed to enhance skin health. Astragalus gombiformis, for example, has shown UV-absorbing and anti-inflammatory properties, while Astragalus…

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