Given the increasing demand for skin whitening and health products, tyrosinase inhibitors have garnered significant attention in the food, pharmaceutical, and cosmetic industries. However, conventional inhibitors like arbutin, hydroquinone, and kojic acid often face limitations due to issues with solubility,…
The cosmetic industry is experiencing a growing demand for natural and sustainable ingredients, driven by increasing consumer awareness regarding the potential concerns associated with synthetic compounds. Simultaneously, the human skin’s microbiome, while crucial for health, can also harbor pathogenic organisms…
Skin health is closely tied to collagen production, which maintains firmness and elasticity. Cell therapies often leverage the “secretome,” a cocktail of growth factors, proteins, and signaling molecules released by cells. Among these, extracellular vesicles (EVs)—especially bacterial EVs (bEVs)—have emerged…
Skin injuries, from simple cuts to chronic ulcers, affect up to 6% of the population and often result in poor healing due to infection, oxidative stress, and extracellular matrix breakdown. Chronic wounds are particularly challenging, often complicated by biofilm-forming fungi…
Consumers are increasingly shifting toward clean-label skincare, pressuring formulators to replace synthetic preservatives and antioxidants. While conventional additives like parabens and formaldehyde releasers offer some protection, they come with safety concerns—including irritation, allergies, cytotoxicity, and environmental burden. The need for…
Psoriasis is a chronic autoimmune skin disease marked by inflammation, scaling, and impaired skin integrity. It stems from immune dysregulation, particularly involving Th17 cells and overexpression of IL-17A. One of the lesser-known facets of psoriasis is the disruption it causes…
The skin acts as our first line of defense, shielding us from environmental stressors like UV radiation, which can cause photodamage, inflammation, and even cancer. UVB exposure leads to excess reactive oxygen species (ROS), triggering inflammatory cascades and compromising skin…
Acne vulgaris is a chronic inflammatory skin condition that often begins with one key trigger—excess sebum production driven by androgenic activity. While many topical treatments manage acne by targeting bacteria or inflammation, few directly address the root cause: overactive sebaceous…
Cellulite—also called Edematous Fibrosclerotic Panniculopathy (EFP), gynoid lipodystrophy, or “orange peel” skin—is a common condition affecting up to 90% of post-pubertal women, especially on the thighs and buttocks. Though harmless, its visual presentation can negatively affect self-esteem. Current non-invasive treatments…
The cosmetic industry constantly balances innovation with the pressing need for validated safety. While commercial excitement surrounds new raw materials, scientific scrutiny often lags behind, especially when it comes to safety claims. Animal-derived ingredients like PDRN raise concerns around ethics,…