Scientific Updates

Effect of Staphylococcus aureus Colonization and Immune Defects on the Pathogenesis of Atopic Dermatitis

Atopic dermatitis (AD) is a chronic skin disease marked by inflammation, pruritus (itchiness), and skin barrier dysfunction. While the exact cause of AD is unclear, epidermal barrier impairment, immune dysregulation, microbial imbalance (dysbiosis), and environmental triggers play key roles in…

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Fact-checking Cosmetic Trends: Systematic Review of the Use of Topical Astragalus Derivatives to Treat Dermatologic Conditions

Astragalus, a genus with over 2000 species, has been used in traditional Chinese medicine for centuries. Known for its diverse health benefits, is believed to enhance skin health. Astragalus gombiformis, for example, has shown UV-absorbing and anti-inflammatory properties, while Astragalus…

Read MoreFact-checking Cosmetic Trends: Systematic Review of the Use of Topical Astragalus Derivatives to Treat Dermatologic Conditions

Hyaluronic Acid-Solid Lipid Nanotransporter Serum for Enhanced Topical Tretinoin Delivery: A Comprehensive Study on Skin Safety and Efficacy

Solid lipid nanotransporters (SLNs) have garnered attention as efficient carriers for drug delivery to the skin, enhancing permeability and stability. Hyaluronic acid (HA) is a well-known moisturizing agent with skin barrier-enhancing properties, making it a suitable candidate for combination with…

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Lotus Sprout Extract Induces Selective Melanosomal Autophagy and Reduces Pigmentation

Skin pigmentation is primarily regulated by melanin production and its accumulation in melanosomes. Hyperpigmentation disorders are commonly treated with agents that inhibit melanin synthesis, such as tyrosinase inhibitors. However, autophagy, a cellular degradation process, has emerged as a potential regulator…

Read MoreLotus Sprout Extract Induces Selective Melanosomal Autophagy and Reduces Pigmentation

Dysbiosis of the Skin and Mucosal Mycobiome in Psoriasis Patients Treated with IL-23 Inhibitors

Psoriasis is a chronic inflammatory skin disease characterized by immune dysregulation, where treatments like IL-23 inhibitors have shown promising results. However, the broader effects of such treatments on the skin’s microbial ecosystem, particularly the mycobiome (the fungal component of the…

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Anti-aging effect of Mustard and Flax Seed Oils-Based Nanoemulsion Gel on Aged Rat Skin Through Antioxidant and Anti-inflammatory Activity

Aging of the skin is a complex biological process influenced by intrinsic and extrinsic factors such as oxidative stress, inflammation, and collagen degradation. One promising approach to combating skin aging involves the use of plant oils rich in unsaturated fatty…

Read MoreAnti-aging effect of Mustard and Flax Seed Oils-Based Nanoemulsion Gel on Aged Rat Skin Through Antioxidant and Anti-inflammatory Activity

Treatment Effects of Two Pharmaceutical Skin Care Creams for Xerotic Feet in Persons with Diabetes: A Double-Blind Randomized Controlled Trial

The prevalence of diabetes mellitus is increasing globally, with diabetic foot ulcers (DFU) being a major complication that often resulted in severe outcomes, including amputations and reduced life expectancy. Foot care with humectants could help improve foot health and prevent…

Read MoreTreatment Effects of Two Pharmaceutical Skin Care Creams for Xerotic Feet in Persons with Diabetes: A Double-Blind Randomized Controlled Trial

A Review of the Anti-Inflammatory Skincare Potential of 𝑬𝒑𝒊𝒍𝒐𝒃𝒊𝒖𝒎 𝒂𝒏𝒈𝒖𝒔𝒕𝒊𝒇𝒐𝒍𝒊𝒖𝒎 (Fireweed) Inspired by Herbal Tradition

Epilobium angustifolium, also known as fireweed, has been traditionally used for skincare benefits, particularly in Northern and Eastern Europe. This review explores the chemical composition, traditional applications, and potential skincare benefits of E. angustifolium, with a focus on its anti-inflammatory…

Read MoreA Review of the Anti-Inflammatory Skincare Potential of 𝑬𝒑𝒊𝒍𝒐𝒃𝒊𝒖𝒎 𝒂𝒏𝒈𝒖𝒔𝒕𝒊𝒇𝒐𝒍𝒊𝒖𝒎 (Fireweed) Inspired by Herbal Tradition

Causal Relationship of Skin Microbiota on Psoriasis: A Mendelian Randomization Study

Psoriasis is a chronic, systemic autoimmune disorder characterized by abnormal skin cell proliferation and inflammation, affecting millions worldwide. Recent research has highlighted the role of the skin microbiota in regulating immune responses, sparking interest in its potential link to psoriasis.…

Read MoreCausal Relationship of Skin Microbiota on Psoriasis: A Mendelian Randomization Study