Photoaging is a progressive and multifactorial skin aging process primarily triggered by prolonged exposure to ultraviolet (UV) radiation. This condition results in significant structural and functional impairments in the skin, including the formation of wrinkles, loss of elasticity, pigmentation irregularities,…
Tyrosinase is a crucial multifunctional enzyme that catalyzes the oxidation of phenolic compounds, playing a significant physiological role in humans. Imbalances or dysregulated expression of this enzyme can lead to various skin disorders, including melanoma, freckles, chloasma, and vitiligo. Given…
Skin aging is a complex biological process influenced by a combination of intrinsic (genetic factors, hormonal fluctuations, cellular senescence) and extrinsic factors (UV radiation, pollution, smoking, diet). These factors lead to visible changes such as wrinkles, loss of elasticity, uneven…
Epidermal Growth Factor (EGF) is a highly promising molecule for the cosmetic industry due to its biological functions, which include promoting cell growth, proliferation, differentiation, and survival, as well as stimulating collagen synthesis and accelerating wound healing processes. These properties…
Atopic dermatitis (AD) is a widespread, chronic inflammatory skin condition affecting millions globally, including children and adolescents, significantly impacting patients’ quality of life. It is characterized by impaired skin barrier function, leading to intense itching (pruritus), dry skin (xerosis), and…
Hydrogels represent a promising class of drug carriers for dermatological applications. They are characterized as specific, three-dimensional hydrophilic networks of polymers that maintain a stable structure despite high water content. Their favorable properties, such as plasticity, bio- and mucoadhesiveness, good…
The skin, serving as the body’s primary barrier, is constantly exposed to various environmental aggressors, with ultraviolet radiation (UVR) being one of the most significant threats. Long-term exposure to UVR is a major contributor to skin aging (photoaging) and carcinogenesis,…
The industrial processing of widely consumed Cucurbitaceae fruits, such as watermelon (Citrullus lanatus), melon (Cucumis melo), and pumpkin (Cucurbita pepo), generates substantial quantities of seed by-products. These residues, often discarded or relegated to low-value uses like animal feed or biofuel,…
Skin aging is a multifaceted biological process influenced by both intrinsic factors, such as genetics and hormonal changes, and extrinsic factors like ultraviolet (UV) radiation, environmental pollution, and lifestyle choices. This complex process results in a progressive decline in the…
The production of pomegranate juice generates a significant quantity of waste, with peels constituting approximately 26–30% of the overall fruit weight. This biowaste presents an environmental challenge but also a potential resource. Pomegranate peels have been identified as a rich…