Scientific Updates

Evaluating Coffee and Rosemary Extracts as Sustainable Alternatives to Synthetic Preservatives

Preservatives play a crucial role in extending the shelf life and ensuring the safety of pharmaceuticals, cosmetics, and food products. However, synthetic preservatives often raise safety concerns, including skin irritation, endocrine disruption, and microbiome alteration. As consumer demand for sustainable…

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Unlocking the Potential of Prunus Leaf Extracts as Sustainable Antioxidants in Topical Skincare Formulations

With increasing consumer demand for natural, eco-friendly skincare, repurposing agricultural by-products has gained attention. Plum plants (Prunus spp.), though economically important, leave behind discarded leaves that contribute to environmental waste. Rich in phenolic and flavonoid compounds like rutin, these leaves…

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Effects of Betulinic Acid and Ursolic Acid on IL-17-Induced CCL20 Release in Normal Human Epidermal Keratinocytes

Psoriasis is a chronic inflammatory skin condition primarily driven by IL-17, which stimulates excessive keratinocyte proliferation and inflammatory cytokine release. One key chemokine, CCL20, further promotes immune cell infiltration, worsening inflammation. Current treatments, though effective, pose challenges like high costs,…

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AdhPep3: A Novel Peptide-Based Therapeutic for Rosacea Targeting Inflammation, Angiogenesis, and Skin Barrier Dysfunction

Rosacea is a chronic inflammatory skin condition marked by persistent redness, visible blood vessels, and facial lesions, affecting approximately 5.5% of the global population. Triggers include UV exposure, heat, spicy food, and genetic factors. At the molecular level, excess activation…

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The Cosmeceutical and Dermatological Potential of Olive Mill Wastewater: A Sustainable and Eco-Friendly Source of Natural Ingredients

Olive mill wastewater (OMWW), a major byproduct of olive oil production, has long been considered an environmental pollutant. However, its rich phenolic content, surpassing even that of olive oil, is now gaining attention for its dermatological potential. These bioactive compounds…

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