The human skin serves as an essential shield against the external world, constantly facing environmental assaults and microbial threats. When this vital barrier is compromised, it can lead to various skin conditions, impacting physical well-being and psychological health. Traditional treatments…
With the rise of antimicrobial resistance, there’s an urgent need for alternative therapeutic agents. Natural compounds from medicinal plants, particularly those used in traditional medicine, have garnered interest for their potential to combat resistant pathogens. Mangifera zeylanica, a Sri Lankan…
Acne vulgaris is one of the most common global skin conditions, affecting around 85% of individuals aged 12–25. It results from chronic inflammation in the pilosebaceous units and is influenced by various internal and external factors such as hormones, stress,…
Atopic dermatitis (AD) is a chronic inflammatory skin condition marked by itching, erythema, and recurrent flare-ups that impact quality of life significantly. Traditional treatments like topical corticosteroids and emollients provide symptomatic relief, but long-term control and relapse prevention remain a…
The skin barrier serves as the body’s primary defense against environmental insults such as ultraviolet (UV) radiation. Exposure to UV light, particularly UVB, is a significant factor contributing to skin barrier damage, leading to conditions like oxidative stress, inflammation, photoaging,…
Fungal skin infections are a growing concern due to rising resistance and limited new antifungal agents. Candida spp., especially Candida albicans and the increasingly common C. glabrata, cause superficial infections like cutaneous candidiasis, which can lead to itching, inflammation, and…
Skin is more than a physical barrier—it’s a neurosensory and immunologically active organ with a deep, bidirectional link to the brain. Emotional states can visibly manifest on the skin through flare-ups, inflammation, and chronic conditions like rosacea or atopic dermatitis.…
Skin aging, a multifactorial and progressive process, is heavily influenced by extrinsic factors such as ultraviolet B (UVB) radiation and oxidative stress caused by hydrogen peroxide (H₂O₂). These stressors accelerate the accumulation of senescent cells and reactive oxygen species (ROS),…
Atopic dermatitis (AD) is a chronic inflammatory skin condition known for its complex etiology and frequent flare-ups. Traditionally, research into AD has focused on the epidermal microbiota, especially the dominance of Staphylococcus aureus and loss of beneficial skin commensals. However,…
The skin microbiome plays a critical role in maintaining skin health, but imbalances involving pathogenic bacteria like Staphylococcus aureus and Staphylococcus epidermidis can lead to common skin issues such as acne, dermatitis, and wound infections. As the demand for microbiome-friendly,…