Chronic dermatological conditions, notably acne vulgaris, androgenetic alopecia (AGA), and alopecia areata (AA), represent a significant burden worldwide, affecting hundreds of millions of individuals and substantially impairing quality of life. Acne alone ranks among the leading causes of disability-adjusted life…
Curcumin (Cur), a naturally occurring polyphenolic compound derived from Curcuma longa, is highly valued in cosmeceutical formulations due to its potent anti-inflammatory and antioxidant properties. Cur plays a multifaceted role in skincare, helping to protect against oxidative stress and premature…
Skin disorders such as photoaging, sunburn, hyperpigmentation, and carcinogenesis represent significant global health and cosmetic challenges, especially as exposure to ultraviolet (UV) radiation intensifies. Sunscreen formulations are essential tools designed to prevent photodamage and deliver therapeutic benefits. However, the reliance…
Acne is a pervasive skin disorder linked to the pilosebaceous components of the skin (hair follicles and oil glands). It manifests clinically through seborrhea and inflammatory or non-inflammatory lesions, often resulting in scarred skin. Acne is highly prevalent among adolescents,…
Epidermal photoinflammation has been identified as an atypical pathological response that poses a growing global threat to human health and well-being. The skin’s protective barrier, primarily relying on the stratum corneum, is disrupted by excessive external stimuli. Among these stimuli,…
Skin aging is driven by both intrinsic chronologic processes and extrinsic factors, primarily photoaging due to ultraviolet (UV) exposure. This degradation manifests as wrinkles, sagging, laxity, and uneven texture, underpinned by structural changes in the extracellular matrix (ECM). Critical components…
Ginkgo biloba L. leaves contain important bioactive compounds, including flavonoids, organic acids, and terpenoids, and extracts from the plant have traditionally been used in medicine. Recently, Ginkgo biloba extracts have garnered renewed attention for their potential benefits, particularly in protecting…
The human skin acts as a barrier, but it is constantly exposed to the environment and remains vulnerable to microbial infections. Skin infections, characterized by symptoms like pain, swelling, and redness, are commonly caused by bacteria or fungi. One prevalent…
The skin microbiome, which includes commensal microorganisms, is integral to maintaining skin health and homeostasis. An imbalance in this microbial community, known as skin dysbiosis, is associated with numerous dermatological issues, including acne vulgaris, atopic dermatitis, psoriasis, wound infections, and…
Chronic exposure to UV radiation poses a significant threat to skin health, as it accelerates the breakdown of collagen and elastin fibers, resulting in premature aging symptoms like wrinkles, loss of elasticity, and age spots. Effective protection against UV-induced skin…