Category Scientific Updates

Hyaluronic Acid-Solid Lipid Nanotransporter Serum for Enhanced Topical Tretinoin Delivery: A Comprehensive Study on Skin Safety and Efficacy

Solid lipid nanotransporters (SLNs) have garnered attention as efficient carriers for drug delivery to the skin, enhancing permeability and stability. Hyaluronic acid (HA) is a well-known moisturizing agent with skin barrier-enhancing properties, making it a suitable candidate for combination with…

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Lotus Sprout Extract Induces Selective Melanosomal Autophagy and Reduces Pigmentation

Skin pigmentation is primarily regulated by melanin production and its accumulation in melanosomes. Hyperpigmentation disorders are commonly treated with agents that inhibit melanin synthesis, such as tyrosinase inhibitors. However, autophagy, a cellular degradation process, has emerged as a potential regulator…

Read MoreLotus Sprout Extract Induces Selective Melanosomal Autophagy and Reduces Pigmentation

Dysbiosis of the Skin and Mucosal Mycobiome in Psoriasis Patients Treated with IL-23 Inhibitors

Psoriasis is a chronic inflammatory skin disease characterized by immune dysregulation, where treatments like IL-23 inhibitors have shown promising results. However, the broader effects of such treatments on the skin’s microbial ecosystem, particularly the mycobiome (the fungal component of the…

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Anti-aging effect of Mustard and Flax Seed Oils-Based Nanoemulsion Gel on Aged Rat Skin Through Antioxidant and Anti-inflammatory Activity

Aging of the skin is a complex biological process influenced by intrinsic and extrinsic factors such as oxidative stress, inflammation, and collagen degradation. One promising approach to combating skin aging involves the use of plant oils rich in unsaturated fatty…

Read MoreAnti-aging effect of Mustard and Flax Seed Oils-Based Nanoemulsion Gel on Aged Rat Skin Through Antioxidant and Anti-inflammatory Activity

Treatment Effects of Two Pharmaceutical Skin Care Creams for Xerotic Feet in Persons with Diabetes: A Double-Blind Randomized Controlled Trial

The prevalence of diabetes mellitus is increasing globally, with diabetic foot ulcers (DFU) being a major complication that often resulted in severe outcomes, including amputations and reduced life expectancy. Foot care with humectants could help improve foot health and prevent…

Read MoreTreatment Effects of Two Pharmaceutical Skin Care Creams for Xerotic Feet in Persons with Diabetes: A Double-Blind Randomized Controlled Trial

A Review of the Anti-Inflammatory Skincare Potential of 𝑬𝒑𝒊𝒍𝒐𝒃𝒊𝒖𝒎 𝒂𝒏𝒈𝒖𝒔𝒕𝒊𝒇𝒐𝒍𝒊𝒖𝒎 (Fireweed) Inspired by Herbal Tradition

Epilobium angustifolium, also known as fireweed, has been traditionally used for skincare benefits, particularly in Northern and Eastern Europe. This review explores the chemical composition, traditional applications, and potential skincare benefits of E. angustifolium, with a focus on its anti-inflammatory…

Read MoreA Review of the Anti-Inflammatory Skincare Potential of 𝑬𝒑𝒊𝒍𝒐𝒃𝒊𝒖𝒎 𝒂𝒏𝒈𝒖𝒔𝒕𝒊𝒇𝒐𝒍𝒊𝒖𝒎 (Fireweed) Inspired by Herbal Tradition

Causal Relationship of Skin Microbiota on Psoriasis: A Mendelian Randomization Study

Psoriasis is a chronic, systemic autoimmune disorder characterized by abnormal skin cell proliferation and inflammation, affecting millions worldwide. Recent research has highlighted the role of the skin microbiota in regulating immune responses, sparking interest in its potential link to psoriasis.…

Read MoreCausal Relationship of Skin Microbiota on Psoriasis: A Mendelian Randomization Study

Could Trifluoromethyl Phenethyl Mesalazine (TFM) Be the Ultimate Antioxidant to Combat Skin Aging?

Skin aging is driven by oxidative stress, leading to wrinkles, pigmentation, and inflammation. Researchers explored the possible action of trifluoromethyl phenethyl mesalazine (TFM), an antioxidizing agent, on skin aging processes. TFM demonstrated strong free radical scavenging abilities, inhibited melanin production,…

Read MoreCould Trifluoromethyl Phenethyl Mesalazine (TFM) Be the Ultimate Antioxidant to Combat Skin Aging?

Evaluation of Biotechnological Active Peptides Secreted by 𝑺𝒂𝒄𝒄𝒉𝒂𝒓𝒐𝒎𝒚𝒄𝒆𝒔 𝒄𝒆𝒓𝒆𝒗𝒊𝒔𝒊𝒂𝒆 with Potential Skin Benefits

Bioactive peptides secreted by microorganisms like Saccharomyces cerevisiae are gaining traction in cosmetics for their antimicrobial, antioxidant, anti-inflammatory, and anti-collagenase (ACE) properties. These peptides address skin concerns such as aging, inflammation, and wound healing, making them valuable in skincare. Researchers…

Read MoreEvaluation of Biotechnological Active Peptides Secreted by 𝑺𝒂𝒄𝒄𝒉𝒂𝒓𝒐𝒎𝒚𝒄𝒆𝒔 𝒄𝒆𝒓𝒆𝒗𝒊𝒔𝒊𝒂𝒆 with Potential Skin Benefits

A cutting-edge atomization-based methodology for enhancing formulation ability to resist photoaging

Photoaging results from prolonged exposure to ultraviolet (UV) radiation, leading to skin issues like hyperpigmentation, rough texture, dryness, and loss of elasticity. Current treatments can be invasive and have limited effectiveness. Researchers in this study, propose a novel, non-invasive method…

Read MoreA cutting-edge atomization-based methodology for enhancing formulation ability to resist photoaging