Skin pigmentation is primarily regulated by melanin production and its accumulation in melanosomes. Hyperpigmentation disorders are commonly treated with agents that inhibit melanin synthesis, such as tyrosinase inhibitors. However, autophagy, a cellular degradation process, has emerged as a potential regulator…
Psoriasis is a chronic inflammatory skin disease characterized by immune dysregulation, where treatments like IL-23 inhibitors have shown promising results. However, the broader effects of such treatments on the skin’s microbial ecosystem, particularly the mycobiome (the fungal component of the…
Aging of the skin is a complex biological process influenced by intrinsic and extrinsic factors such as oxidative stress, inflammation, and collagen degradation. One promising approach to combating skin aging involves the use of plant oils rich in unsaturated fatty…
The prevalence of diabetes mellitus is increasing globally, with diabetic foot ulcers (DFU) being a major complication that often resulted in severe outcomes, including amputations and reduced life expectancy. Foot care with humectants could help improve foot health and prevent…
Epilobium angustifolium, also known as fireweed, has been traditionally used for skincare benefits, particularly in Northern and Eastern Europe. This review explores the chemical composition, traditional applications, and potential skincare benefits of E. angustifolium, with a focus on its anti-inflammatory…
Psoriasis is a chronic, systemic autoimmune disorder characterized by abnormal skin cell proliferation and inflammation, affecting millions worldwide. Recent research has highlighted the role of the skin microbiota in regulating immune responses, sparking interest in its potential link to psoriasis.…
Skin aging is driven by oxidative stress, leading to wrinkles, pigmentation, and inflammation. Researchers explored the possible action of trifluoromethyl phenethyl mesalazine (TFM), an antioxidizing agent, on skin aging processes. TFM demonstrated strong free radical scavenging abilities, inhibited melanin production,…
Bioactive peptides secreted by microorganisms like Saccharomyces cerevisiae are gaining traction in cosmetics for their antimicrobial, antioxidant, anti-inflammatory, and anti-collagenase (ACE) properties. These peptides address skin concerns such as aging, inflammation, and wound healing, making them valuable in skincare. Researchers…
Photoaging results from prolonged exposure to ultraviolet (UV) radiation, leading to skin issues like hyperpigmentation, rough texture, dryness, and loss of elasticity. Current treatments can be invasive and have limited effectiveness. Researchers in this study, propose a novel, non-invasive method…
Vitamin E, a potent antioxidant, is essential for human health, especially in protecting cells from oxidative damage. Its applications range from oral supplementation for overall health to topical usage for skin care. Vitamin E, with its antioxidant and photoprotective characteristics,…