Skin aging is a multifactorial process influenced by intrinsic factors like genetics and hormonal changes, as well as extrinsic factors such as UV radiation, pollutants, and lifestyle choices. These factors contribute to signs of aging, including wrinkles, loss of elasticity,…
Coconut oil, derived from the Cocos nucifera tree, has been an integral part of tropical and subtropical cultures, revered for its versatility and health benefits. Its dried kernel, or copra, serves as the primary source for oil extraction. Coconut oil is…
Psoriasis, a chronic and immune-mediated skin disorder affecting millions worldwide, is driven by a complex interplay of genetic, environmental, and immune factors. The IL-17/IL-23 axis plays a central role in the disease’s pathogenesis, making it a critical target for therapeutic…
Porokeratoses are a diverse group of rare keratinization disorders that present unique clinical challenges. These disorders often manifest as papules progressing into annular plaques with central atrophy and scaling edges. Pathogenesis involves both genetic susceptibility and environmental triggers, including…
Introduction This study aimed to evaluate the potential of whole human saliva as an anti-acne agent against bacteria responsible for acne vulgaris (AV). Human saliva was selected due to its physiological and antioxidant properties, containing beneficial secretory molecules such as…
The skin, the body’s largest organ, plays a crucial role in protecting internal tissues and regulating moisture and body temperature. However, it also presents a significant barrier to the penetration of many compounds, especially due to the structure of the…
Halobacteria trueperi TCI66207, an extremophilic microorganism thriving in high-salt environments, produces extracellular polysaccharides known for their promising anti-inflammatory, antioxidant, and anti-aging properties. This study focuses on the strain H. trueperi TCI66207, isolated from the Pacific Ocean at a depth of 662 m…
Agave sisalana, traditionally used in folk medicine for treating various ailments, discards 95% of its leaf biomass as waste. This study explores the potential of its sapogenin-rich residue, particularly hecogenin and tigogenin, for anti-inflammatory and analgesic uses. Steroidal saponins from…
Jujube (Ziziphus jujuba Mill.) extracts are rich in antioxidants and have potential anti-aging effects, targeting fine lines, wrinkles, and skin hydration. Key components include antioxidants, fatty acids, vitamins, and polysaccharides, which improve skin texture, promote collagen synthesis, regulate inflammation, protect…
Skin aging, accelerated by UV-induced reactive oxygen species (ROS), leads to wrinkles and loss of elasticity. Astaxanthin and zeaxanthin (AZ-NE), potent antioxidants, offer significant protection against ROS and have potential in anti-aging skincare. This study evaluates the stability, skin penetration,…